This winery carves up a part of its name with Chateau Grand-Puy-Ducasse.

Grand Puy is the name of a low gravelly hill which used to be owned in its entirety by the same estate. Parts of the vineyards on this hill were sold in 1750 to a man by the name Pierre Ducasse.

The estate containing the remaining vineyards, the present day Chateau Grand-Puy-Lacoste, has been known under several names which have changed when daughters of the owning family have married. It was known as Saint-Guiron in the mid-19th century after a marriage to a monsieur de Saint-Guiron, and acquired its present name one generation later when a daughter married a man by the name François Lacoste.

Chateau Grand-Puy-Lacoste is also the name of the red wine produced by this property. The wine produced here was classified as one of eighteen Cinquièmes Crus (Fifth Growths) in the Bordeaux Wine Official Classification of 1855.