A charming story is told in the Florentine Histories, written in 1838 by Giovanni Cavalcanti, in which the wine of the vineyards of Nozzole occupies a central role. Castruccio Castracani, born in 1281, was a youth of great virtue but deprived of life's material riches. He thus decided to devote himself to service in the military. On his voyage through the countryside to join the troops, he arrived at Nozzole, where he encountered a poor peasant innkeeper.

In more recent history, the Nozzole estate was owned by Letizia Rimediotti-Mattioli, who with her husband, a Florentine cavalry officer in World War II, turned their interests from animal breeding and grain cultivation of to vineyards and wine. The estate is located in an impressively rugged mountainous area of great melancholy beauty and covers roughly 1,000 acres, of which approximately a third are planted in vines and olive groves.

The Rimediottis produced wine which for several years was commercialized by the Folonari family, who subsequently purchased the estate in 1971. Situated north of the village of Greve in Chianti at Passo dei Pecorai, the Nozzole estate is now one of the principal holdings of Tenute di Ambrogio and Giovanni Folonari. For further background on the estates of Ambrogio and Giovanni Folonari.

The Nozzole estate produces a Chianti Classico Riserva and a single-vineyard wine from the superb "La Forra" parcel. Cabernet Sauvignon, cultivated principally in another parcel of the estate planted in 1981 called "Il Pareto," yields a pure Cabernet wine first produced in the 1987 vintage. The principal white vineyards of the Nozzole estate, the "Le Bruniche" and "Casa Vecchia" vineyards, once planted in Trebbiano Toscano and Malvasia, were replanted to Chardonnay in the early 1980s. These vineyards now produce Nozzole Le Bruniche, a distinctive, pure varietal Chardonnay.